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Efficiency of Absorption and Metabolic Conversion of Quercetin and Its Glucosides in Human Intestinal Cell Line Caco-2

โœ Scribed by Kaeko Murota; Sumie Shimizu; Hitomi Chujo; Jae-Hak Moon; Junji Terao


Book ID
115568525
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
131 KB
Volume
384
Category
Article
ISSN
0003-9861

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Transport of levovirin prodrugs in the h
โœ Fujun Li; Lei Hong; Cheng-I Mau; Rebecca Chan; Than Hendricks; Chuck Dvorak; Cal ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 142 KB ๐Ÿ‘ 1 views

The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi