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Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients

✍ Scribed by Odunsi, K.; Matsuzaki, J.; Karbach, J.; Neumann, A.; Mhawech-Fauceglia, P.; Miller, A.; Beck, A.; Morrison, C. D.; Ritter, G.; Godoy, H.


Book ID
111674254
Publisher
National Academy of Sciences
Year
2012
Tongue
English
Weight
786 KB
Volume
109
Category
Article
ISSN
0027-8424

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## Abstract We conducted a phase I clinical trial of a cancer vaccine using a 20‐mer NY‐ESO‐1f peptide (NY‐ESO‐1 91–110) that includes multiple epitopes recognized by antibodies, and CD4 and CD8 T cells. Ten patients were immunized with 600 ΞΌg of NY‐ESO‐1f peptide mixed with 0.2 KE Picibanil OK‐432