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Efficacy of two mandibular advancement appliances in the management of snoring and mild-moderate sleep apnea: A cross-over randomized study

✍ Scribed by Luc Gauthier; Luc Laberge; Michel Beaudry; Mario Laforte; Pierre H. Rompré; Gilles J. Lavigne


Book ID
116884549
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
202 KB
Volume
10
Category
Article
ISSN
1389-9457

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Background. Metrifonate is a long-lasting acetylcholinesterase inhibitor being developed for the symptomatic treatment of Alzheimer's disease (AD). Objectives. This study compared the ecacy, tolerability and safety of two doses of metrifonate in patients with mild-to-moderate AD, over a 26-week tre