Efficacy of thalidomide- or lenalidomide-based therapy in proliferative multiple myeloma
β Scribed by Kapoor, P; Kumar, S; Mandrekar, S J; Laumann, K M; Dispenzieri, A; Lacy, M Q; Dingli, D; Gertz, M A; Kyle, R A; Greipp, P R
- Book ID
- 109887477
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 167 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0887-6924
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The introduction of thalidomide, lenalidomide, and bortezomib has changed the way that multiple myeloma (MM) is treated and has greatly improved survival outcomes. These novel agents are often used in combination with conventional drugs, such as dexamethasone, to optimize clinical responses; however
## Abstract ## BACKGROUND Recently, the authors reported improved time to disease progression (TTP) with a combination of pegylated liposomal doxorubicin (PLD) and bortezomib compared with bortezomib alone in a phase 3 randomized trial in patients with recurrent/refractory multiple myeloma (MM). I
## Abstract Hemizygous deletion of 17p (del(17p)) has been identified as a variable associated with poor prognosis in myeloma, although its impact in the context of thalidomide therapy is not well described. The clinical outcome of 85 myeloma patients with del(17p) treated in a clinical trial incor