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Efficacy of tenofovir disoproxil fumarate at 240 weeks in patients with chronic hepatitis B with high baseline viral load

✍ Scribed by Gordon, Stuart C.; Krastev, Zahary; Horban, Andrzej; Petersen, Jörg; Sperl, Jan; Dinh, Phillip; Martins, Eduardo B.; Yee, Leland J.; Flaherty, John F.; Kitrinos, Kathryn M.; Rustgi, Vinod K.; Marcellin, Patrick


Book ID
120278342
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
817 KB
Volume
58
Category
Article
ISSN
0270-9139

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Tenofovir disoproxil fumarate (TDF) is a nucleotide analogue with potent activity against human immunodeficiency virus type 1 and hepatitis B virus (HBV). To date, no reports of HBV clinical resistance to TDF have been confirmed. In two phase 3 studies (GS-US-174-0102 and GS-US-174-0103), 375 hepati