Efficacy of sublingual apomorphine in idiopathic Parkinson's disease
โ Scribed by F. Durif; F. Serre; D. Deffond; A. Eschalier; M. Tournilhac
- Book ID
- 115885260
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 220 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0014-2999
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๐ SIMILAR VOLUMES
We tested a novel preparation of a sublingual apomorphine hydrochloride tablet (APO) in 10 patients with advanced Parkinson's disease complicated by motor fluctuations. After a dose titration, patients took either 40 mg APO three times per day alternating with levodopa doses (eight patients) or six
## Abstract A new formulation of a sublingual tablet with 10 mg apomorphine was examined in 13 patients with Parkinson's disease. Vitamin C (250 mg) was added sublingually to lower the salivary pH. Four patients received sublingual apomorphine and nine received sublingual apomorphine as well as vit