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Efficacy of repeated adenoviral suicide gene therapy in a localized murine tumor model

✍ Scribed by Eric S Lambright; Seth D Force; Michael E Lanuti; Dahlia S Wasfi; Kunjlata M Amin; Steven M Albelda; Larry R Kaiser

Book ID
117032480
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
265 KB
Volume
70
Category
Article
ISSN
0003-4975

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## Abstract ## Background Gliomas are invasive malignant tumours with poor prognosis. Combination of gene directed enzyme pro‐drug therapy with existing treatment modalities might open new therapeutic potentials. ## Methods Murine glioma 261 (Gl261) cells were transduced with an adenoviral vecto