Efficacy of Mucoadhesive Hydrogel Microparticles of Whey Protein and Alginate for Oral Insulin Delivery
✍ Scribed by Déat-Lainé, Emmanuelle; Hoffart, Valérie; Garrait, Ghislain; Jarrige, Jean-François; Cardot, Jean-Michel; Subirade, Muriel; Beyssac, Eric
- Book ID
- 120366791
- Publisher
- Springer US
- Year
- 2012
- Tongue
- English
- Weight
- 785 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0724-8741
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Hydrogels comprised of poly(methacrylic acid) grafted with poly(ethylene glycol) (P(MAA-g-EG)) were characterized and examined for their potential as oral insulin carriers. Insulin loaded polymer (ILP) samples were made using two different polymer formulations. The values for the effective molecular
## Abstract This manuscript describes the development of a new porous, flexible bilaminated film for buccal protein administration by a simple and mild casting procedure. It consists of a mucoadhesive layer (chitosan‐ethylenediaminetetraacetic acid hydrogel film) containing protein drugs and an imp