Efficacy of microfiltration in decreasing propofol-induced pain

✍ Scribed by A. F. Davies; B. Vadodaria; B. Hopwood; T. Dexter; D. Conn

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 151 KB
• Volume: 57
• Category: Article
• ISSN: 0003-2409
• DOI: 10.1046/j.1365-2044.2002.02602.x

✦ Synopsis

Summary In a randomised, double‐blinded, two‐centre trial we evaluated the effect of a microbiological filter (Supor^®^, Pall Life Sciences) on propofol injection pain. We studied 336 unpremedicated adult patients, who graded pain experienced during induction of anaesthesia with propofol on a 4‐point verbal rating scale. Use of the microfilter reduced both the incidence and severity of propofol injection pain (p < 0.001). Incidence of severe pain in the filter group was 2.4% compared with 16.6% in the control group. Overall, 33.7% in the filter group experienced pain compared with 62.1% in the control group. A microbiological filter may provide a non‐pharmacological alternative to a lidocaine/propofol mixture for reducing injection pain. It would also reduce the risk of any glass and bacterial contamination.