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Efficacy of memantine in people with moderate to severe Alzheimer's disease with and without background donepezil therapy: Pooled analysis of four randomized trials

✍ Scribed by Graham, Stephen; Hendrix, Suzanne; Miller, Michael; Pejovic, Vojislav; Tocco, Michael

Book ID: 123503037
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 49 KB
Volume: 9
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2013.05.1348

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## Abstract ## Background There have been very limited investigations of cholinesterase inhibitor therapy in more advanced stages of Alzheimer's disease (AD). The efficacy and safety of donepezil were evaluated in __post hoc__ analyses of a subgroup of patients with more severe AD (standardized Mi