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Efficacy of ivermectin in the treatment of concomitant Mansonella perstans infections in onchocerciasis patients

✍ Scribed by H. Schulz-Key; W. Albrecht; C. Heuschkel; P.T. Soboslay; M. Banla; H. Görgen

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
488 KB
Volume
87
Category
Article
ISSN
0035-9203

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✍ Kwablah Awadzi; Simon Kwaku Attah; Ebenezer Thomas Addy; Nicholas Obuobisa Opoku 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 630 KB

Ivermectin, at the standard dose of 150 cLg/kg bodyweight, does not kill the adult worms of Onchocerca volvulus and does not disrupt embryogenesis or spermatogenesis. Repeated standard doses, if maintained, arrest microfilarial production but result in only a mild-to-modest macrofilaricidal effect.