✦ LIBER ✦

Efficacy of intravesical mitomycin C in the treatment of superficial transitional cell carcinoma of the urinary bladder

✍ Scribed by Abraham Pavlotsky; Abraham Eidelman; Frida Barak; Haim Alon; Dr. Yoav Horn

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 301 KB
Volume: 41
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930410106

No coin nor oath required. For personal study only.

✦ Synopsis

We treated 47 patients with recurrent transitional cell carcinoma of the bladder with intravesical chemotherapy. Twenty milligrams of mitomycin C per treatment was introduced 7 days after transurethral resection (TUR) or diagnostic cystoscopy, and was repeated at 2-week intervals for five times followed again by cystoscopy. Two more similar courses were administered for a total of 36 weeks. Clinical data revealed no toxicityrelated symptoms. Cystoscopic follow-up showed a gradual decline in the presence of tumor to a complete response rate of 87.1 % at 36 weeks. Thirteen patients who were previously treatment failures with other drugs responded to mitomycin C.

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