TAKA0 TSUJI,~ SADAHITO SHIN,2 MASASHI TA"03, MICKEY s. URDEA,4 AND JANICE A. KOLBERG4 To clarify the viral factors that may predict the therapeutic effect of interferon (IFN) in chronic hepatitis C (CHC) patients, we investigated the quantitative serum hepatitis C virus (HCV) RNA level, genotype, a
Efficacy of interferon alfa therapy in chronic hepatitis C patients depends primarily on hepatitis C virus RNA level
โ Scribed by Gotaro Yamada; Masahiro Takatani; Fumitoshi Kishi; Michiko Takahashi; Toshihiko Doi; Takao Tsuji; Sadahito Shin; Masashi Tanno; Mickey S. Urdea; Janice A. Kolberg
- Book ID
- 119155924
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 856 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0270-9139
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The quantitation of hepatitis C virus (HCV) viremia RNA is measured by molecular techniques such as comcan be helpful in the diagnosis, therapy, and monitoring petitive reverse-transcription polymerase chain reacof patients with chronic hepatitis C. A sensitive and tion and branched DNA (bDNA) signa
Hepatitis C virus RNA as detected by reverse transcription and nested polymerase chain reaction was monitored in 16 patients with chronic hepatitis C treated with interferon. Hepatitis C virus R N A became undetectable after 4 to 8 wk of interferon administration in 13 of the 16 patients. During 6 m