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EFFICACY OF HIGH-DOSE INTRAVENOUS GAMMAGLOBULIN IN THE MANAGEMENT OF ACQUIRED VON WILLEBRAND'S DISEASE DURING ORTHOPAEDIC SURGERY

✍ Scribed by S. Gross; C. Traulle; J. C. Capiod; B. Roussel; B. Lafon; E. Hayek; J. Dieval; J. Delobel

Book ID
114712811
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
299 KB
Volume
82
Category
Article
ISSN
0007-1048

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## Abstract Acquired von Willebrand disease (aVWD) is a rare bleeding disorder that mimics congenital VWD in previously healthy individuals; it is most frequently associated with monoclonal gammopathy. Hemostatic therapy of aVWD is challenging due to the extremely shortened half‐life of endogenous