Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harboring epidermal growth factor receptor mutations: A pooled analysis of published reports
β Scribed by Takehito Shukuya; Toshiaki Takahashi; Rieko Kaira; Akira Ono; Yukiko Nakamura; Asuka Tsuya; Hirotsugu Kenmotsu; Tateaki Naito; Kyoichi Kaira; Haruyasu Murakami; Masahiro Endo; Kazuhisa Takahashi; Nobuyuki Yamamoto
- Book ID
- 108587028
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 232 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1347-9032
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## Abstract We investigated the relationships between genetic factors and clinical outcome in Japanese nonβsmallβcell lung cancer (NSCLC) patients treated with gefitinib. Ninetyβeight NSCLC patients who had been treated with gefitinib, were screened for mutations in epidermal growth factor receptor
## Abstract ## BACKGROUND. Because the investigation of epidermal growth factor receptor gene (__EGFR__) status as a predictor of gefitinib efficacy in Japanese patients has shown promise, the authors evaluated __EGFR__ mutations and gene amplification in biopsy specimens from Japanese patients wi