Efficacy of dexon microsutures in rat major abdominal vessel anastomosis. I: Application to heterotopic heart transplant
✍ Scribed by Ciro Pempinello; P. Haghighi; Sun Lee; Guy P. Curtis
- Book ID
- 102947850
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 528 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0738-1085
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✦ Synopsis
A total of 52 syngeneic heterotopic heart transplants were performed using 9-0 Dexon microsutures to see if these anastomoses could be tolerable when challenged by the burden of transplanted heart and lung. Eighteen long-term surviving transplants were verified by reliable ECG, Doppler tracings, and direct palpation of the heart grafts. Animals sacrificed at monthly intervals beginning 3 to 6 months posttransplantation were free of thrombus, lung abscesses, and separation at the anastomoses. Even though foreign body reaction was still present up to 5 months posttransplantation, no actual sutures were present after 3 months. From these observations, Dexon microsuture is acceptable in organ transplantation procedures.