Efficacy of denbufylline in patients with multi-infarct dementia
β Scribed by M. O'Connolly; D. Dierdorf; Dr. W. H. Greb; M.-E. R. Mayer; D. Wolf
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 213 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0272-4391
No coin nor oath required. For personal study only.
β¦ Synopsis
The efficacy and tolerance of denbufylline (25 and 50 mg tid for three months) were investigated in 20 inpatients with cerebrovascular disease in a placebo-controlled, doubleblind parallel study. Denbufylline at 50 mg tid significantly improved the mental, emotional, and social capabilities of the patients; tolerance was acceptable.
π SIMILAR VOLUMES
The CT and angiographic appearances in multi-infarct dementia have been compared with those of primary neuronal degeneration. It was possible to make a CT or angiographic diagnosis of multi-infarct dementia in about 40% of patients diagnosed by the ischaemic scoring method of Hachinski et al.
Short-term fluctuation in cognitive functioning was assessed in 13 subjects with presumed multi-infarct dementia (MID) and 16 subjects with presumed dementia of the Alzheimer type (DAT) by administering a short battery of cognitive tests to subjects on three occasions over a period of approximately