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Efficacy of combined therapy of adjuvant arthritis in rats by methotrexate and enkephalin analogues

✍ Scribed by A. Venalis; L. Leonaviciene; V. Astrauskas; R. Bradunaite; D. Vaitkiene; I. Bobrova

Book ID
119578290
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
152 KB
Volume
5
Category
Article
ISSN
0928-4680

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Louvain (LOU) rats were administered either methotrexate (MTX; 0.3 mg/kg/week or 0.8 mg/kg/week intraperitoneally), cyclosporin A (CSA; 4 mg/kg/day or 10 mg/kg/day continuous infusion via osmotic pump), or a combination of both agents. The rats were immunized with native type I1 collagen (CII) to de