Efficacy of colchicine in patients with primary biliary cirrhosis poorly responsive to ursodiol and methotrexate
โ Scribed by Young Mee Lee; Marshall M Kaplan
- Book ID
- 119393793
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 57 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0002-9270
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๐ SIMILAR VOLUMES
Primary biliary cirrhosis frequently progresses despite treatment with ursodeoxycholic acid (UDCA), the only approved therapy. Previous studies suggested that colchicine and methotrexate may improve biochemical tests of liver function, symptoms, and liver histology. The aim of the present study was
We wish to add an additional suggestion to the "AASLD Practice Guidelines: Primary Biliary Cirrhosis" that was published last month in HEPATOLOGY 1 and of which we were coauthors. Approximately 40% of patients with primary biliary cirrhosis (PBC) respond incompletely to treatment with ursodiol. Bec
Primary biliary cirrhosis (PBC) is a chronic, progressive, cholestatic liver disease. Interleukin-lp (JL-lp) may play a role in the pathogenesis of PBC by contributing to altered immune function and fibrosis. Colchicine or methotrexate has some beneficial effects in the treatment of PBC, and also af