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Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

✍ Scribed by Pierre Fenaux; Ghulam J Mufti; Eva Hellstrom-Lindberg; Valeria Santini; Carlo Finelli; Aristoteles Giagounidis; Robert Schoch; Norbert Gattermann; Guillermo Sanz; Alan List; Steven D Gore; John F Seymour; John M Bennett; John Byrd; Jay Backstrom; Linda Zimmerman; David McKenzie; CL Beach; Lewis R Silverman

Book ID: 117784915
Publisher: The Lancet
Year: 2009
Tongue: English
Weight: 232 KB
Volume: 10
Category: Article
ISSN: 1470-2045
DOI: 10.1016/s1470-2045(09)70003-8

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Efficacy of azacitidine compared with th

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

✍ Pierre Fenaux; Ghulam J Mufti; Eva Hellstrom-Lindberg; Valeria Santini; Carlo Fi 📂 Article 📅 2009 🏛 The Lancet 🌐 English ⚖ 232 KB

## Background: Drug treatments for patients with high-risk myelodysplastic syndromes provide no survival advantage. in this trial, we aimed to assess the effect of azacitidine on overall survival compared with the three commonest conventional care regimens. ## Methods: In a phase iii, internation