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Efficacy of a Tyrosine Kinase Inhibitor in Idiopathic Pulmonary Fibrosis

✍ Scribed by Richeldi, Luca; Costabel, Ulrich; Selman, Moises; Kim, Dong Soon; Hansell, David M.; Nicholson, Andrew G.; Brown, Kevin K.; Flaherty, Kevin R.; Noble, Paul W.; Raghu, Ganesh; Brun, Michèle; Gupta, Abhya; Juhel, Nolwenn; Klüglich, Matthias; du Bois, Roland M.


Book ID
120464189
Publisher
Massachusetts Medical Society
Year
2011
Tongue
English
Weight
864 KB
Volume
365
Category
Article
ISSN
0096-6762

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In patients with idiopathic pulmonary fibrosis, nintedanib reduced the decline in FVC, which is consistent with a slowing of disease progression; nintedanib was frequently associated with diarrhea, which led to discontinuation of the study medication in less than 5% of patients.