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Efficacy of a combination thromboxane receptor antagonist and lipoxygenase inhibitor in traumatic shock

✍ Scribed by M.Andrew Levitt; Gregory Stahl; Allan M. Lefer


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
697 KB
Volume
16
Category
Article
ISSN
0300-9572

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas