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Efficacy and toxicity of sunitinib in patients with metastatic renal cell carcinoma with severe renal impairment or on haemodialysis

✍ Scribed by Debra Josephs; Thomas E. Hutson; Charles L. Cowey; Lisa M. Pickering; James M. Larkin; Martin E. Gore; Mieke Van Hemelrijck; David F. McDermott; Thomas Powles; Paramit Chowdhury; Chris Karapetis; Peter G. Harper; Toni K. Choueiri; Simon Chowdhury

Book ID: 110923475
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 212 KB
Volume: 108
Category: Article
ISSN: 1464-4096
DOI: 10.1111/j.1464-410x.2010.09990.x

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## Abstract ## BACKGROUND. In a randomized, phase 3 trial, sunitinib demonstrated superior efficacy over interferon‐alfa as first‐line therapy in patients with metastatic clear‐cell renal cell carcinoma (RCC). On the basis of outcome data from that trial, the authors developed a nomogram for predi