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Efficacy and toxicity of CyberKnife re-irradiation and “dose dense” temozolomide for recurrent gliomas

✍ Scribed by Alfredo Conti; Antonio Pontoriero; Donatella Arpa; Carmelo Siragusa; Chiara Tomasello; Pantaleo Romanelli; Salvatore Cardali; Francesca Granata; Costantino De Renzis; Francesco Tomasello

Publisher: Springer Vienna
Year: 2011
Tongue: English
Weight: 139 KB
Volume: 154
Category: Article
ISSN: 0001-6268
DOI: 10.1007/s00701-011-1184-1

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## Abstract ## BACKGROUND Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short‐lived. Temozolomide may prove more effective in combination with other agents. Therefore, combination oral chemotherapy for these patients is a particularly