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Efficacy and tolerability of sumanirole in restless legs syndrome: A phase II, randomized, double-blind, placebo-controlled, dose–response study

✍ Scribed by Diego Garcia-Borreguero; John Winkelman; Alieu Adams; Amanda Ellis; Mark Morris; Janice Lamb; Gary Layton; Mark Versavel

Book ID: 116883936
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 239 KB
Volume: 8
Category: Article
ISSN: 1389-9457
DOI: 10.1016/j.sleep.2006.05.018

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## Abstract Iron deficiency may exacerbate symptoms in the Restless Legs Syndrome (RLS). We investigated the effect of intravenous iron sucrose or placebo on symptoms in patients with RLS and mild to moderate iron deficit. Sixty patients with primary RLS (seven males, age 46 (9) years, S‐ferritin ≤