Efficacy and tolerability of recombinant human granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related leukopenia and fever
β Scribed by Biesma, Bonne; de Vries, Elisabeth G.E.; Willemse, Pax H.B.; Sluiter, Willem J.; Postmus, Pieter E.; Limburg, Pieter C.; Stern, Angelika C.; Vellenga, Edo
- Book ID
- 121926972
- Publisher
- Elsevier Science
- Year
- 1990
- Weight
- 687 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0277-5379
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## Abstract Twenty children 1β17 (median, 5.5) years of age received GMβCSF during chemotherapyβinduced neutropenia at the dose of 5 ΞΌg/kg/day, continued until the absolute neutrophil count (ANC) exceeded 500 Γ 10^6^/liter. Twelve children with solid tumors received GMβCSF after courses of conventi
Combinations of low dosages of purified recombinant human (rh) macrophagecolony stimulating factor (M-CSF; also termed CSF-1) and rh granulocyte-colony stimulating factor (G-CSF) were compared alone and in combination for their influence on the cycling rates and numbers of bone marrow and splenic gr