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Efficacy and safety of ursodeoxycholic acid in primary, type IIa or IIb hypercholesterolemia: A multicenter, randomized, double-blind clinical trial

โœ Scribed by Manoela F.B. Braga; Michael G.A. Grace; Jacques Lenis; Frank P. Kennedy; Avery L. Teplinsky; Ghislaine Roederer; Pasquale J. Palumbo; Patrick Colin; Lawrence A. Leiter


Book ID
118213413
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
116 KB
Volume
203
Category
Article
ISSN
0021-9150

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Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile acids are retained in the liver and are hepatotoxic. Ursodeoxycholic acid is the least-known hepatotoxic bile acid, h