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Efficacy and safety of rasburicase, a recombinant urate oxidase (Elitek™), in the management of malignancy-associated hyperuricemia in pediatric and adult patients: final results of a multicenter compassionate use trial

✍ Scribed by Jeha, S; Kantarjian, H; Irwin, D; Shen, V; Shenoy, S; Blaney, S; Camitta, B; Pui, C-H


Book ID
110056090
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
98 KB
Volume
19
Category
Article
ISSN
0887-6924

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Rasburicase (recombinant urate oxidase)
✍ André Bosly; Anne Sonet; C. Ross Pinkerton; Geoffrey McCowage; Dominique Bron; M 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 100 KB

## Abstract ## BACKGROUND Hyperuricemia and tumor lysis syndrome (TLS) are serious complications that can occur during chemotherapy for hematologic malignancies, even if standard management procedures, including administration of allopurinol, are undertaken. Rasburicase, a recombinant urate oxidas