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Efficacy and Safety of Pegylated Interferon Alfa-2a or Alfa-2b Plus Ribavirin for the Treatment of Chronic Hepatitis C in Children and Adolescents: A Systematic Review and Meta-analysis

✍ Scribed by Druyts, E.; Thorlund, K.; Wu, P.; Kanters, S.; Yaya, S.; Cooper, C. L.; Mills, E. J.


Book ID
121363325
Publisher
University of Chicago Press
Year
2012
Tongue
English
Weight
107 KB
Volume
56
Category
Article
ISSN
1058-4838

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Chronic hepatitis C virus (HCV) infection is usually asymptomatic in children, but significant liver disease may occur. We evaluated the efficacy, safety, and pharmacokinetics of interferon alfa-2b and ribavirin in children with chronic HCV. We determined the optimal ribavirin dose in an initial coh