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Efficacy and safety of liposomal anthracyclines in Phase I/II clinical trials

✍ Scribed by David S. Alberts; Franco M. Muggia; James Carmichael; Eric P. Winer; Mohammad Jahanzeb; Alan P. Venook; Keith M. Skubitz; Edgardo Rivera; Joseph A. Sparano; Nicholas J. Dibella; Simon J. Stewart; John J. Kavanagh; Alberto A. Gabizon

Book ID
114473606
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
529 KB
Volume
31
Category
Article
ISSN
0093-7754

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## Abstract ## Purpose To assess the safety, effective dose, and efficacy of a novel hepatobiliary MR contrast agent Gd‐DTPA‐DeA for imaging liver tumors, from the clinical phase I and phase II trials in Japan. ## Materials and Methods In a phase I trial, 33 healthy volunteers were intravenously