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Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial

✍ Scribed by Josef S Smolen; Joachim R Kalden; David L Scott; Blaz Rozman; Tore K Kvien; Arvi Larsen; Iris Loew-Friedrich; Christine Oed; Ronald Rosenburg

Book ID
117311622
Publisher
The Lancet
Year
1999
Tongue
English
Weight
111 KB
Volume
353
Category
Article
ISSN
0140-6736

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## Abstract ## Objective Current treatment options for psoriatic arthritis (PsA) are limited. Leflunomide, an oral pyrimidine synthesis inhibitor, is highly effective in the treatment of rheumatoid arthritis, and small studies have suggested similar efficacy in PsA. We undertook this double‐blind,