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Efficacy and safety of fenwal cs-3000 plateletpheresis performed at a rapid donor blood flow rate: Rapid plateletpheresis with fenwal cs-3000

✍ Scribed by Dr. Ronald G. Strauss; Gerald A. Ludwig; M. Joleen Randels; Diane C. Winegarden


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
232 KB
Volume
6
Category
Article
ISSN
0733-2459

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✦ Synopsis


Results of 3,2 14 plateletpheresis proccdures, using the Fenwal CS-3000 cell separator, were revicwcd to determine the effects on performance when the donor blood flow rate was increased by 30% (i.e., to 65 mlimin instead of 50 mlimin). Ninety-two percent (2,962 of 3.214) of procedures completed the rapid flow protocol, and results were compared with those reported by others using the more conventional blood flow rates of 32-55 mlimin. When the rapid flow procedure was used, mean platelet yields (4.07 X 10") and leukocyte contamination (2.65 X 10') were satisfactory. and major donor reactions were infrequent (0.6% of procedures). Thus. CS-3000 plateletpheresis can be performed at a relatively rapid, donor blood flow rate of 65 mlimin to shorten the procedure and make it more appealing to donors.