The objective of this study was to assess the tolerability and efficacy of rivastigmine in a group of patients with probable dementia with Lewy bodies (DLB), using an open label study. Open label treatment was with rivastigmine up to maximum tolerated dose (mean 9.6 mg daily, range 3-12 mg). Eleven
Efficacy and safety of donepezil in patients with dementia with Lewy bodies: Preliminary findings from an open-label study
โ Scribed by SATORU MORI; ETSURO MORI; EIZO ISEKI; KENJI KOSAKA
- Book ID
- 108961961
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 138 KB
- Volume
- 60
- Category
- Article
- ISSN
- 1323-1316
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๐ SIMILAR VOLUMES
## Abstract ## Background This open label study was designed to assess the effects of donepezil treatment, its withdrawal and subsequent recommencement on cognitive functioning, behaviour and parkinsonian symptoms in patients with probable dementia with Lewy bodies (DLB) and with Parkinson's disea
## Abstract ## Objective This 132โweek, openโlabel extension study assessed the longโterm efficacy and safety of donepezil in 579 patients with mild to moderate Alzheimer's disease (AD) who had previously participated in a 24โweek doubleโblind study of 5 or 10โmg/day donepezil __vs__ placebo. ##
In several retrospective post-mortem studies, patients meeting clinical criteria for Alzheimer's disease (AD) who gained the greatest cognitive beneยฎt from treatment with an acetylcholinesterase (AChE) inhibitor were found to have neocortical Lewy bodies accompanying classical AD neuropathology. Thi