## Abstract ## Objective To evaluate the efficacy and safety of golimumab in patients with ankylosing spondylitis (AS) in the GO‐RAISE study. ## Methods Patients with active AS, a Bath AS Disease Activity Index (BASDAI) score ≥4, and a back pain score of ≥4 were randomly assigned in a 1.8:1.8:1
✦ LIBER ✦
Efficacy and safety of adalimumab in patients with ankylosing spondylitis: Results of a multicenter, randomized, double-blind, placebo-controlled trial
✍ Scribed by Désirée van der Heijde; Alan Kivitz; Michael H. Schiff; Joachim Sieper; Ben A. C. Dijkmans; Jürgen Braun; Maxime Dougados; John D. Reveille; Robert L. Wong; Hartmut Kupper; John C. Davis Jr.
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 143 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
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## Abstract ## Objective There is increasing evidence that tumor necrosis factor α (TNFα) is centrally involved in the pathogenesis of ankylosing spondylitis (AS) and other spondylarthritides. This study was designed to investigate the efficacy of anti‐TNFα therapy with etanercept, a 75‐kd recepto