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Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia

✍ Scribed by Evelyn Depoortere; Jean-Paul Guthmann; Jacinthe Pressé; Naawa Sipilanyambe; Esther Nkandu; Suna Balkan; Philippe Eldin De Pécoulas; Dominique Legros

Book ID
110869659
Publisher
John Wiley and Sons
Year
2005
Tongue
French
Weight
95 KB
Volume
10
Category
Article
ISSN
1360-2276

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A randomized safety and tolerability trial of artesunate plus sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine alone for the treatment of uncomplicated malaria in Gambian children
✍ J.F. Doherty; A.D. Sadiq; L. Bayo; A. Alloueche; P. Olliaro; P. Milligan; L. von 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 474 KB

Artemisinin derivatives, such as artesunate, have a short half-life and very rapid anti-malarial activity. Theoretically, using such agents in conjunction with well-established anti-malarial drugs such as sulfadoxine-pyrimethamine may reduce the rate of drug resistance. Such a combination has not pr