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Efficacy and augmentation during 6 months of double-blind pramipexole for restless legs syndrome

✍ Scribed by Birgit Högl; Diego Garcia-Borreguero; Claudia Trenkwalder; Luigi Ferini-Strambi; Wayne Hening; Werner Poewe; Stefanie S. Brenner; Mandy Fraessdorf; Michael Busse; Stefan Albrecht; Richard P. Allen


Book ID
116885032
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
342 KB
Volume
12
Category
Article
ISSN
1389-9457

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Efficacy of pramipexole in restless legs
✍ Wolfgang H. Oertel; Karin Stiasny-Kolster; Bettina Bergtholdt; Yngve Hallström; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB

## Abstract We evaluated the efficacy of pramipexole versus placebo in restless legs syndrome (RLS) for 6 weeks. Overall, 345 patients were randomly assigned in a 1:2 ratio to receive either placebo (n = 115) or pramipexole (n = 230) with a starting dose of 0.125 mg/day. The dose was individually o