Effects on serum albumin of response and relapse to lamivudine in patients with chronic hepatitis B
β Scribed by J.M. Hui; J. George; C. Liddle; R. Lin; D. Samarasinghe; E. Crewe; G. Farrell
- Book ID
- 119526113
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 156 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0168-8278
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## Abstract __Background__: Cytokines are known to play critical roles in the pathogenesis of chronic hepatitis B (CHB). However, the relationship between cytokines and treatment responses to drugs for CHB is not clearly defined yet. We measured the serum cytokine levels of interleukin (IL)β1Ξ±, ILβ
Nucleoside analogues can induce mitochondrial dysfunction leading to severe clinical syndromes. Lamivudine, a new nucleoside analogue, is an active inhibitor of hepatitis B viral replication without apparent clinical toxicity. To assess subclinical mitochondrial toxicity, we studied the morphology a