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Effects on human lymphocyte transformation of drugs inhibiting lipoxygenase enzyme pathways of arachidonic acid metabolism

โœ Scribed by M.A. Bray; M.J.H. Smith


Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
84 KB
Volume
2
Category
Article
ISSN
0192-0561

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Effect of dihomogammalinolenic acid and
โœ L. Iversen; K. Fogh; K. Kragballe ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 478 KB

The purpose of the present study was to determine the effect of the n-6 fatty acid, dihomogammalinolenic acid (DGLA, 20 : 3, n-6) on arachidonic acid (AA) (C20:4) metabolism by human peripheral mononuclear leukocytes (HPML). After incubation of HPML with A23187 (5 ~tM) and DGLA, the cyclooxygenase (