Effects on cimetidine bioavailability of metoclopramide and antacids given two hours apart

The effect of antacid, metoclopramide, a

The effect of antacid, metoclopramide, and propantheline on the bioavailability of metoprolol and atenolol

✍ Carl G. Regardh; Per Lundborg; Bengt A. Persson 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 409 KB 👁 2 views

## Abstract Concomitant administration of antacid increased the maximum concentration (__Cp__~max~) and the area under the plasma concentration‐time curve (AUC) of 100 mg oral dose of metoprolol by 25 per cent (__p__< 0.05) and 11 per cent (__p__ < 0.1) respectively. For atenolol the opposite effec