Effects ofPKCαantisense RNA on human breast cancer cell proliferation and expression ofcyclinD1andCDK4
✍ Scribed by Jianli Sang; Yongchao Wang
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 298 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1001-6538
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## Abstract To better understand the multiple hormonal control of the expression of apolipoprotein D (apo‐D) and gross cystic disease fluid protein‐15 (GCDFP‐15, also designated prolactin‐inducible protein), which are 2 major proteins found in benign breastdisease fluid, we investigated their regul
Breast cancers frequently over-express a number of growth factor receptors. In addition, elevated src family kinase activity is present in a percentage of these neoplasms and has been implicated in signal transduction in these cells. Therefore, inhibiting tyrosine kinase activity is a potential appr