Effects of flunarizine on rat cerebral c
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Kennet H. Reid; Roger Marrannes; Albert Wauquier
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Article
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1987
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John Wiley and Sons
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English
⚖ 607 KB
Flunarizine was tested using a single dose (40 mglkg IP) and multiple doses (30 mg/kg PO presurgery) in 200-250 g male Wistar rats, using physiological measures related to the rapid ionic shift seen in cerebral cortex following a sudden insult. The threshold for initiation of a spreading depression