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Effects of β-funaltrexamine (β-FNA) on morphine dependence in rats and monkeys

✍ Scribed by Mario D. Aceto; William L. Dewey; P.S. Portoghese; A.E. Takemori


Book ID
115880358
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
404 KB
Volume
123
Category
Article
ISSN
0014-2999

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β-funaltrexamine antagonizes the discrim
✍ Charles P. France; James H. Woods 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 409 KB

Antagonistic actions of the irreversible, mu-selective antagonist beta-funaltrexamine (beta-FNA) were evaluated in pigeons trained to discriminate among intramuscular injections of morphine (5.6 mg/kg), saline, and naltrexone (10.0 mg/kg). Beta-FNA administered alone (1.0 or 10.0 mg/kg) failed to mi