Effects of zonisamide on neurotransmitter release associated with inositol triphosphate receptors
β Scribed by Satoshi Yamamura; Hiromitsu Saito; Noboru Suzuki; Sanae Kashimoto; Tatsuya Hamaguchi; Keiko Ohoyama; Dai Suzuki; Shinich Kanehara; Masanori Nakagawa; Takashi Shiroyama; Motohiro Okada
- Book ID
- 116771233
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 686 KB
- Volume
- 454
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Studies with inβvitroβcultured neurons treated with amyloidβΞ² (AΞ²) peptides demonstrated neuronal loss by apoptosis that is due, at least in part, to the perturbation of intracellular Ca^2+^ homeostasis. In addition, it was shown that an endoplasmic reticulum (ER)βspecific apoptotic pat