𝔖 Bobbio Scriptorium
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Effects of vinblastine, oncodazole, procarbazine, chlorambucil, and bleomycin in vivo on colchicine binding activity of tubulin

✍ Scribed by Ann E. Brodie; Joanne Potter; D.J. Reed


Book ID
118938823
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
415 KB
Volume
24
Category
Article
ISSN
0024-3205

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✍ Mina E. Holm Nygaard; John M. Dornish; Reidar Oftebro; Kjell Undheim πŸ“‚ Article πŸ“… 1986 πŸ› Springer US 🌐 English βš– 948 KB

The effect of 2-(2-thenyl)sulfonyl-5-bromopyrimidine (NY 4137) on cells of the human line NHIK 3025 was investigated. It was shown that NY 4137 induces cell cycle specific inhibition in metaphase. A dose-dependent prolongation of metaphase was found and the fraction of cells able to escape metaphase