## Abstract We have previously reported that hyberbaric oxygen (HBO) improved the survival rate of experimental free flaps. The purpose of this study was to evaluate the effects of combined hypothermia and HBO administered during storage on free flaps and on the xanthine oxidase system in rats. Epi
Effects of venous hypertension on rabbit free flap survival
โ Scribed by Michael D. Rooks; John S. Gould; Victoria Masear; Jack H. Powell; Sheryl Gould
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 714 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0738-1085
No coin nor oath required. For personal study only.
โฆ Synopsis
A two-stage project was developed to study the effect of increased venous pressure on blood flow and survival in microvascular free tissue transfers. A rabbit epigastric fasciocutaneous free flap model was used. The blood flow in the rabbit epigastric free flap is 1.07 +/- 0.06 ml/min. The average venous pressure is 8.6 +/- 1.7 cm water. A logarithmic relationship between blood flow and venous pressure was demonstrated, with a statistically significant decrease in blood flow to 20-35% of the control values when the venous pressure rose above 28-30 cm water. This study stands in support of the tolerance by free tissue transfers of pressures below this range. The results further show a positive correlation between increasing venous pressure and free flap failure.
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