The effect of chronic administration of gamma-vinyl GABA (GVG; vigabatrin) on levels of neurotransmission-related amino compounds was studied in lumbar cerebrospinal fluid of 65 patients with complex partial epilepsy. The first sample of cerebrospinal fluid was taken before a 3-month period of treat
β¦ LIBER β¦
Effects of vagus nerve stimulation on amino acids and other metabolites in the CSF of patients with partial seizures
β Scribed by E. Ben-Menachem; A. Hamberger; T. Hedner; E.J. Hammond; B.M. Uthman; J. Slater; T. Treig; H. Stefan; R.E. Ramsay; J.F. Wernicke; B.J. Wilder
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 474 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0920-1211
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Vigabatrin, as a single oral dose of 50 mg/kg, was administered to 11 patients with drug-refractory complex partial epilepsy. Serial lumbar punctures were performed prior to and 5 times within the first week following treatment. Cerebrospinal fluid (CSF) concentrations of total GABA, free GABA, homo
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