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Effects of U50,488H on locomotor activity in the hamster

✍ Scribed by Paul Schnur; J. Michael Walker

Book ID: 113223693
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 392 KB
Volume: 36
Category: Article
ISSN: 0091-3057
DOI: 10.1016/0091-3057(90)90082-s

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## Opioid receptor agonists (e.g.,488) increase the locomotor activity of preweanling rats, while the same drugs depress the locomotor activity of adults. Curiously, direct stimulation of dopamine (DA) D 2 -like receptors fully attenuates the U-50,488-induced locomotor activity of preweanling rats