The glutathione (GSH) synthesis inhibitor, buthionine sulfoximine (BSO) was tested for cytotoxicity and thiol depletion in murine and human tumor cells in vitro, and for its antitumor activity and toxicity in vivo. The cell lines used in these studies included murine L-1210 leukemia, human RPMI 8226
Effects of Tyrosinase Activity on the Cytotoxicity of 3,4-Dihydroxybenzylamine and Buthionine Sulfoximine in Human Melanoma Cells
β Scribed by PREZIOSO, JOSEPH A. ;FITZGERALD, GEORGE B. ;WICK, MICHAEL M.
- Book ID
- 111259403
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 555 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0893-5785
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