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Effects of triptolide on degeneration of dendritic spines induced by Aβ1–40injection in rat hippocampus

✍ Scribed by Wan, Bin; Hu, Xiaoling; Nie, Jing; Zhou, Ming; Yang, Baolin; Li, Yaobing; Wen, Wei; Lü, Cheng

Book ID: 121581196
Publisher: Springer Milan
Year: 2013
Tongue: English
Weight: 550 KB
Volume: 35
Category: Article
ISSN: 1590-1874
DOI: 10.1007/s10072-013-1463-0

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## Abstract Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline due to neuronal loss and neural network dysfunction. It has been postulated that progressive neuronal loss in AD is consequence of the neurotoxic properties of the amyloid‐β peptide (Aβ). In the p