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Effects of Topiramate on Sustained Repetitive Firing and Spontaneous Recurrent Seizure Discharges in Cultured Hippocampal Neurons

✍ Scribed by Robert J. DeLorenzo; Sompong Sombati; Douglas A. Coulter


Book ID
109108316
Publisher
Wiley (Blackwell Publishing)
Year
2000
Tongue
English
Weight
481 KB
Volume
41
Category
Article
ISSN
0013-9580

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## Abstract The effects of adrenergic receptor stimulation on spontaneous synaptic transmission were investigated in cultured rat hippocampal neurons by recording spontaneous excitatory and inhibitory postsynaptic currents (sEPSC and sIPSC). Noradrenaline (NA) inhibited sEPSC in a concentration‐dep